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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16cbc28127acb31814f1953c0cce193ec882d9eb05637be4a244d9dbc1c21177' 
  AND token = '2pzZx2GzXaRdQz7NNJB+4wsG3+F/hnMTbc7Bk+5bOlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}