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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3b8f28cf40d4e36b18435ceb313a9ccb10d35b1e9471014b40e351d98b7eafe' 
  AND token = 'sEmOT2wMd4+oITGmbC9hkfXQPf3PrOr9SqSlU3R5Q+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}