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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e2d3491a310539e9f332f078854c70728782ed4fdf44cb0d8acf8464c46ee35' 
  AND token = '6oI7yPiEh57F0nIzBkVoWBTuPWoguEz50vQKHAI0qQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}