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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8abecb243fdc99c1c9101500c92fada77ed1fdeacad6a67863b767d555bb83b' 
  AND token = 'PRkjG4hbb30lt3PJh7y2upkBS5TagQgCXdcMu9duSVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}