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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb8240d013375d34b6ce0a43b0839d5c081a69bffa3767979faf771d5f19579' 
  AND token = 'DY8hJYyFMb1fYA4ocU3IZ+763KyirMonHYIYRr2cckE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}