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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24776c9117f9f563b7ff955adf583c9ada2ec78a53c76a7859b3d59afa493b8f' 
  AND token = '5dPDRA4aBRbYWDaV2njqzptbea9djhc/7uW9yIgFbU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}