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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54103218dc0e061d522a5c92c20e253aa9a23cf0ab467e26c1144008d06db62d' 
  AND token = 'GTItgt5Jsu5pHgp9WkGngVgI5eSKS9jIRPw00pk65+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}