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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a268125896d5cf7d13b2f72fc307002536bfc25947b6e65ea2477cad4e029a' 
  AND token = '2jFU85S6THPR8xl2o8bA/WhU/1VGYje6ezkfo3kdFhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}