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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb4a5edf80e64d12aad761247821df21eb55f48e315383d91cd452d7f9b8b5e0' 
  AND token = 'VzF9UYmdchKyDfaP/fkr6qwgx12syhmybli4uUOuVQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}