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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '825696d5fb501ba0947c51fddfab7b1be74e07e1b7dddc57b666cbc0c970284f' 
  AND token = 'gcTnFDYLAPkqf1U3rpqbW3PCSjg8NT2rrE0wiSGTm/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}