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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac016ad0b3ca81bde57c0513f99ed8ac0efc7ca374440566d5209d2896648895' 
  AND token = 'CFeS+hEjjTGYf1+pwSa0olMat3+EGuyi+LC1ZRq9mBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}