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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e56129a594580ece7a9db72beb5c8490103bb047a132576ff12d8d6e2e5e8c71' 
  AND token = 'COtD7/Hj/znxc3uI4N0/S5sDZad+lkF6V1WI3XcyVGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}