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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d6b8a373269affc37b643bdfe4adabf284dbd707d68f04ec4445c8a7b4a28ad' 
  AND token = 'V+nb85/BEIW8PtWiAbO+rEb2KmOZriEcXIF0/AhQjUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}