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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15613e2e858c22d02af659fb10b02c75cccd1a52176542ec8b14d186042bda87' 
  AND token = 'LB4zG1E8M3s8gZPdGa+BnnNHI5LfrdwYWhn7/CYZNaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}