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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4949484cf7e6e990552c1446e79b21ce045b7d71701c19b14a41e1ea5c7a5ae1' 
  AND token = 'FcHdIsJwT7bq/hpXTEeQOe9N4cYYxo99JngmpFGGecw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}