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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2286a53075106d6288237747fb6a1e1f5a3a66d7c1d76866fb0e0b835980e82d' 
  AND token = 'rUIyWzyD3J0ucpkBfUuSkKeMe2KPGfe8ygylLHRF6jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}