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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5c3c268ea99cb144f6b96062d03f74b287b7af8ed261fba2224b000114febf6' 
  AND token = 'XQ4eVZNURc3o6+Ws1BSHjSAB3924mU9RhV1AlktaMgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}