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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc493bb6d0761f0be55afe83ffceac8133b1c92729a50d90ca422c74b5c7ada' 
  AND token = 'GfBG7B0AGqfiucYreQwak0GIvNTPz78QqwALe44hklM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}