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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e85ab3e4eb86cecf6243dc6ee562492913761c60d32b402ca0c886da960efab' 
  AND token = '9xaOHTjpyNSDoP3TMGpz/McLh/8sw3KLEMQ7rS1g95U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}