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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d26b779770fc07b4b05c7d8401a5f47fd3c5b34fc0d115efc8030ae50b67b08' 
  AND token = 'hoZTzHAbgR1abvd1QnI2VZ9v2logUuKgP/5QXEeg5jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}