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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03fb97b62ec402609c5e1338ba0f82cdc0999f70b810975d45eb86542518872e' 
  AND token = 'WuPUAo0Yxr61YqgsWryJ2l+6JWcMeP+yJGA0IXYFJA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}