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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffcf0024e4f6f7bc4bd949d4840f36940b470ddbed1d4240ce1aee8b384d4097' 
  AND token = 'jgzwfotXCdZK4O5g2tpER9M+vhKhDCS0UZqrr6p9I0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}