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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3749be3ac8ef3eb3630d71725f8e89da55cea987f3b00493ad08ec09e5c5983d' 
  AND token = '01E4fsA934W3e+/NmKSdlWcA4tDQtJfhJuLRPlCSMFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}