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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f6fcbfd0d76700d258f7af782bb0baa33518bc9053c562a2732b3c33b961300' 
  AND token = 'dTH7gydOsX1uQk4mv1fDaOdqBvyYG3jH3entk64roLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}