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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4e470b42def02e2e9e81f055bdee14438c6032547c95145037ddbd28b11cc5' 
  AND token = 'vMu/YY6mJlK65CfiUQ62R4gR5A9CMOT24YxnslYfbpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}