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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99250456f5f2ae19ff84a09e5415e0f4f9cf187c134c68c2cf26f0b9bdaf34ac' 
  AND token = 'uStanP+XhHRd6RKwUZ7E9A1miMpQYMaTpUvi8m88x3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}