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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88efe874836095fc1c3e55cef22b7731d9384a2e85bf67f30f891db9292c17f4' 
  AND token = 'XQ62zW6TOFX0JYYwPR9Juy1MSxY+iXlQb5ZtI4Ntm2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}