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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2581c6c13a8c38a6a9c5b3daee5f0aa356399aeef7c6ee9f057ab5043b1ed052' 
  AND token = '30fB10lcCll26JGV1YeLrtEod+gW/H/vZjglFU2M3fU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}