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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43275785000c40ac17e6b42fba27d04970ea6ad18023ee25ab4b7df9675e1d8' 
  AND token = 'z9fVauQKlX5SvJ0o8y1M/xtK4sBeHzkSHiNZ5ssxBHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}