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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5caa6ef2f63d4af0a96abd7c4a874dd182b41c40913855c1339558c558f1fb4e' 
  AND token = 'cLKNndsyZHTlc1Mc/PZfHl6L2EqcNjXkeca/dBawGyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}