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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df4175262e9cd649c2a58cac00173c398002c3ef49ab955c358af7d53da18371' 
  AND token = 'fGRnu6EPwA9Dwzuh+1iHmLcQDF17CjDIn4easjthXYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}