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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7d34382f4260f8f6c96724deb0f11890520e9695ae0c0e6e4cb4aa805603d2' 
  AND token = 'dmDsnyBS4VL6baApHhLQ3i+cR4OAQ9IBc3OZn507M64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}