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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53eb2991dc4eb1c8e0efdb19e15668b700072363603281135ba76ad20437ce10' 
  AND token = 'oWp47UH510nv9BTnXIEaMPDJvv7p643Yey39UDz7Cco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}