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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5d4d986951a7243be59cc1dbb0b59e9ca24ac47ea164296e1000100a2b3308d' 
  AND token = 'NOlmehkqNc7d8R+gljh1sciYvIgB3DxZ03V+s3Q+9KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}