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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c606ee9b3c84ed138a1d7188f1edde0d7c151822a8ec5228faf62bb8a402c2c9' 
  AND token = 'dw4q1eCFvf4Rnj2Eee/7HLxKeQQkgzsmEVTIa2lW7Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}