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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac8d14df0c60eb8b17c09933195a593afc8d75181a4914967a8e895ab16988c' 
  AND token = '9HMlpXtqy/glfR2yleEN0q+ROzEzi8aytYq+PPK8zmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}