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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a424e2f94c3ed6145f729dde5e06ee9dc4284ae91d3c24380a00b16c0f26f4d' 
  AND token = 'jLtCEupfMSzcPpT91Mx5cla9SsFxxmrhYWRoAoiZtMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}