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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ff16e8e354aeabf4134595a2e18299b858eb5876496b56a919b10c7933fe33' 
  AND token = 'YEiP+1qb3kZPj8NY3eHqQ81LcYtil3Y6W97MR9bum4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}