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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b92aa88d89248fbfe2463a7617041d8085a85ee1b15f99a996128444435d93' 
  AND token = 'AvkFSsUbr6vlmZhMSNRKF4msf2dRBud7IbbFjodNxmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}