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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb39eaa443e1ab4480b6c7b9bc376a00e60d04051b27a989793e6786fdcca845' 
  AND token = 'mdOH7+/kkURV11pkq9NaTwgtZhMWZPu8ldbfvpQ77JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}