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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1da61a9433c76ff4719f9caffd69b1c48678e5d52f885025616ebfcadeecd497' 
  AND token = '20W2TyAIiozMJi6suQtT0HiyAv4O3PDZYtsC8LjFcog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}