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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc2ad4b791286660c3f25eead804b42554a37db6de8b712af642b6261904651' 
  AND token = 'MyaWVE3ApCOzheXsh8u3pF95JNc7EpeAMdl+S2w0oBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}