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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7316bb6babd514237134ca1642ab43c229e3a34bd2b18dad0fa6c63db9cfbc81' 
  AND token = 'W1iSK4q2nqhqykQ+6ffXSuNWLDk9z5G9h1CvTSRZqaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}