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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29301ea0357cff6b8123bbb7ce0a546d31540988e9a4a3254c6c5b6dee5c8239' 
  AND token = 'dmyKO6Q+aWPF+ZgR2+08JFeb/LZVMeT3+Lm/zJobLDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}