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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37498db1044090bb4dcb597ec6e8da779cb6795ad43f52c14c4dbb23532a0498' 
  AND token = '0dIX9I6+jslyioXBkPIhhvI3dRAPO3S7CpLeaz+id8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}