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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71b84155c46d48ca9c305f047c0b0c568b777af1e8a7e0cf9289bf9814070495' 
  AND token = 'ZuADOzFXVg9txG38YsMFDdXOX5XrXWgJSYzTUyIkZbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}