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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2362d7442bd431495dc21aa7953ed30dfb13626b46b3a3c15401091f912435b8' 
  AND token = 'TUSP2W2OE3vloE1GaRy/MsIw/qgOcKgpOzI9rSwJZ60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}