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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb6651cee68cb2b50b39954dec0436bb823e2c011df5ffe0a2223c096572b49d' 
  AND token = '+gqRKiyrg4Qd1O82KIF5ZCds1/dVROs7tC+Pzr26GPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}