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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77afca469c6fe3ccaa57eac861a2f270a5e4ae615685a2589320d4d52b224cf6' 
  AND token = 'GmgfhJ7L1xdToGGqwlHLoHp1uZajdC1uwk22M2lg2Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}