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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d644b735bd336afa30864705c7da8d9b90b5d41589efdec87361b832d0687d' 
  AND token = 'AQehWfrORFLIi4cwWeEeAl7GH9C1Oxp9RmeHfhJcdYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}